Maleic Anhydride

Maleic Anhydride

SCHEMBL7556955

C=C(CC)C(=O)OCCCCCC.O=C1C=CC(=O)O1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
NAAA Q02083 3/20 0.44
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ESR1 P03372 3/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
EPHX1 P07099 1/20 0.38
GPR84 Q9NQS5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL9188369 0.88 THRB (0.37) TSHRALDH1A1
Styrene SCHEMBL8571228 0.87 TSHR (0.40) TSHRALDH1A1LMNATP53CYP3A4
Maleic Anhydride SCHEMBL26180922 0.87 TSHR (0.71) TSHRNAAAALDH1A1LMNATP53
Maleic Anhydride SCHEMBL27560872 0.87 TSHR (0.71) TSHRNAAAALDH1A1LMNATP53
Maleic Anhydride SCHEMBL8721383 0.87 TSHR (0.71) TSHRNAAAALDH1A1LMNATP53
Maleic Anhydride SCHEMBL6702917 0.87 TSHR (0.71) TSHRNAAAALDH1A1LMNATP53
SCHEMBL375676 0.84 TSHR (0.69) TSHRNAAAALDH1A1LMNARAD52
SCHEMBL11803516 0.84 TSHR (0.69) TSHRNAAAALDH1A1LMNARAD52
SCHEMBL3503962 0.84 TSHR (0.69) TSHRNAAAALDH1A1LMNARAD52
SCHEMBL374874 0.84 TSHR (0.69) TSHRNAAAALDH1A1LMNARAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020077395-A1 Stabilization of aqueous emulsion polymers NATALE MARCIE (US) 2002-06-20 US disclosed
US-6362259-B1 MIXTURE OF EPICHLOROHYDRIN AND ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER COGNIS CORPORATION 2002-03-26 US disclosed
EP-1003606-A4 ALKYLPOLYGLYCOSIDE CONTAINING SURFACTANT BLENDS FOR EMULSION POLYMERIZATION HENKEL CORP (US) 2000-09-13 EP disclosed
US-6117934-A OF UNSATURATED MONOMERS. HENKEL CORPORATION (US) 2000-09-12 US disclosed
EP-1003606-A2 ALKYLPOLYGLYCOSIDE CONTAINING SURFACTANT BLENDS FOR EMULSION POLYMERIZATION HENKEL CORPORATION (US) 2000-05-31 EP disclosed
WO-1998033876-A9 ALKYLPOLYGLYCOSIDE CONTAINING SURFACTANT BLENDS FOR EMULSION POLYMERIZATION 1998-12-10 WO disclosed
WO-1998033876-A2 ALKYLPOLYGLYCOSIDE CONTAINING SURFACTANT BLENDS FOR EMULSION POLYMERIZATION HENKEL CORPORATION (US) 1998-08-06 WO disclosed