Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20507216 | 0.81 | CHRM4 (0.66) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL4182416 | 0.78 | MAPK1 (0.62) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL4001173 | 0.77 | MAPK1 (0.61) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL18711906 | 0.77 | MAPK1 (0.60) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL18702273 | 0.73 | SMN1; SMN2 (0.55) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL26106993 | 0.73 | MAPK1 (0.60) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL14825371 | 0.72 | HTT (0.56) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL13034821 | 0.72 | LMNA (0.58) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL17007428 | 0.70 | SMN1; SMN2 (0.67) | HTTMAPK1MEN1KMT2ACHRM4 | |
| SCHEMBL27750094 | 0.69 | LMNA (0.57) | HTTMAPK1MEN1KMT2ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |