⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633155 | 0.62 | — | — | |
| SCHEMBL993044 | 0.62 | POLB (0.31) | — | |
| SCHEMBL8080950 | 0.62 | — | — | |
| SCHEMBL9782227 | 0.60 | — | — | |
| SCHEMBL8391431 | 0.58 | POLB (0.37) | — | |
| SCHEMBL9633938 | 0.58 | — | — | |
| SCHEMBL993272 | 0.58 | PIK3CD (0.47) | — | |
| SCHEMBL2491333 | 0.57 | — | — | |
| SCHEMBL11850299 | 0.56 | — | — | |
| SCHEMBL8264560 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | claimed |
| EP-0578761-B1 | ENZYMATIC PROCESS FOR THE PRODUCTION OF CEFONICID | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6071712-A | Enzymatic process for the production of cephalosporins | SMITHKLINE BEECHAM CORPORATION (US) | 2000-06-06 | — | — | US | disclosed |
| US-5705645-A | Hereroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5420277-A | BACTERICIDE INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5318963-A | Heterocyclic hydrazide derivatives of monocyclic β-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5290929-A | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5250691-A | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0531976-A1 | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0243924-B1 | 2-OXO-1-(SUBSTITUTED PHOSPHOROUS)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4551277-A | 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid | E. R. SQUIBB & SONS, INC. (US) | 1985-11-05 | — | — | US | disclosed |
| US-4551276-A | 2-Oxoazetidin-1-yloxymethyl sulfonic acid and analogs | E. R. SQUIBB & SONS, INC. (US) | 1985-11-05 | — | — | US | disclosed |
| US-4548747-A | 3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4548751-A | (2-Oxo-1-azetidinyloxy)-2-propenoic acid | E. R. SQUIBB & SONS, INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4534896-A | 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid) | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0138407-A1 | Azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0135814-A1 | 1-(1H-tetrazol-5-ylalkoxy)-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0132356-A1 | Process for preparing 2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| EP-0124123-A1 | 3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |