Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7557248

N.N.NC(N)=C(N)N.NC(N)=C(N)N.NC(N)=C(N)N

nearest known ligand 0.33

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
ATR Q13535 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2024277 1.00 TSHR (0.33) TSHRATMATRALDH1A1LMNA
SCHEMBL866054 0.91
Ethylene SCHEMBL11388516 0.87
SCHEMBL275325 0.83 TSHR (0.33) TSHRATMATRALDH1A1LMNA
Iodide SCHEMBL17025881 0.83
Hydrochloric Acid SCHEMBL14782379 0.83
Hydrochloric Acid SCHEMBL10972400 0.83 LMNA (0.36) TSHRATMATRALDH1A1LMNA
Hydrochloric Acid SCHEMBL16761049 0.83 LMNA (0.36) TSHRATMATRALDH1A1LMNA
Water SCHEMBL2435455 0.83 TSHR (0.33) TSHRATMATRALDH1A1LMNA
SCHEMBL9635020 0.83 TSHR (0.33) TSHRATMATRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980360-B1 A PROCESS FOR THE PREPARATION OF 1,4,7,10-TETRAAZACYCLODODECANE BRACCO INT BV (NL) 2002-07-17 EP claimed