Adenine

Adenine

SCHEMBL755727

NC(=O)c1cccnc1.Nc1ncnc2nc[nH]c12.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.46
PI4K2B Q8TCG2 2/20 0.46
PI4K2A Q9BTU6 2/20 0.46
PI4KB Q9UBF8 2/20 0.46
LMNA P02545 2/20 0.46
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
SARM1 Q6SZW1 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.46
SIRT6 Q8N6T7 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
SIRT3 Q9NTG7 1/20 0.46
SIRT5 Q9NXA8 1/20 0.46
SIRT4 Q9Y6E7 1/20 0.46
DRD3 P35462 1/20 0.46
XDH P47989 1/20 0.46
LRRK2 Q5S007 1/20 0.46
MKNK1 Q9BUB5 1/20 0.42
BRD4 O60885 4/20 0.41
CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL19057041 0.96 PI4KA (0.44) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL1408059 0.94 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL27528672 0.94 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL15700 0.91 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL22748487 0.91 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL2564210 0.91 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL23531102 0.90 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL11807683 0.90 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL1324561 0.90 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7712108 0.90 PI4KA (0.54) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512486-B2 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2023-07-12 EP claimed
EP-3512486-B1 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2020-10-21 EP claimed
EP-3512486-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'Oreal (FR) 2019-07-24 EP claimed
WO-2018050504-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-03-22 WO claimed
US-6750038-B1 Rapid antibiotic susceptibility test ESSENTIAL THERAPEUTICS, INC. 2004-06-15 US claimed
US-5460830-A Biochemically active agents for chemical catalysis and cell receptor activation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-24 US claimed
US-5460831-A Targeted transfection nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-24 US claimed
EP-3512486-B2 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2023-07-12 EP disclosed
CN-114796107-A Tobramycin sulfate injection containing nicotinide diphosphate and preparation method thereof 西藏邦臣药业集团有限公司 2022-07-29 CN disclosed
CN-107428744-B Novel heterocyclic compounds and their use in medicine and cosmetics 盖尔德马研究及发展公司 2021-09-24 CN disclosed
EP-3512486-B1 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2020-10-21 EP disclosed
CN-110621304-A Combination of active ingredients, composition comprising the same and use thereof in the treatment of sarcopenia 阿法玛公司 2019-12-27 CN disclosed
EP-3512486-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'Oreal (FR) 2019-07-24 EP disclosed
EP-0726767-A1 BIOCHEMICALLY ACTIVE AGENTS FOR CHEMICAL CATALYSIS AND CELL RECEPTOR ACTIVATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-08-21 EP disclosed
US-5506420-A PREVENT DENATURIZATION OF ELECTRONICALLY ACTIVE BIOCHEMICAL MOLECULE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-04-09 US disclosed
US-5462751-A Biological and pharmaceutical agents having a nanomeric biodegradable core THE REGEANTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-31 US disclosed
US-5460830-A Biochemically active agents for chemical catalysis and cell receptor activation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-24 US disclosed
US-5460831-A Targeted transfection nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-10-24 US disclosed
WO-1995018234-A1 METHOD FOR ENZYMATICALLY ASSAYING CREATININE OR THE AMMONIUM ION AND REAGENT KIT FOR CARRYING OUT SAID METHOD PASTEUR SANOFI DIAGNOSTICS (FR) 1995-07-06 WO disclosed
WO-1995012392-A1 BIOCHEMICALLY ACTIVE AGENTS FOR CHEMICAL CATALYSIS AND CELL RECEPTOR ACTIVATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-05-11 WO disclosed