Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555222 | 0.80 | HPRT1 (0.47) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL131080 | 0.76 | MAPK1 (0.55) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL28962436 | 0.76 | MAPK1 (0.55) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL133155 | 0.73 | MEN1 (0.52) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL58539 | 0.73 | MAPK1 (0.57) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL130420 | 0.73 | KMT2A (0.59) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL131366 | 0.73 | ALDH1A1 (0.59) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL3289050 | 0.73 | MAPK1 (0.52) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL131079 | 0.73 | MAPK1 (0.52) | MAPK1MEN1KMT2AMAPTS100A4 | |
| SCHEMBL4507358 | 0.73 | MAPK1 (0.52) | MAPK1MEN1KMT2AMAPTS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221044-A2 | MONOFLUORINATED POLYCYCLIC AROMATIC COMPOUNDS AND THE USE THEREOF AS ADDITIVE POLYCYCLIC AROMATIC COMPOUNDS IN PHYSICAL, CHEMICAL AND BIOLOGICAL PROCESSES | Luthe, Gregor (DE) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001029555-A2 | MONOFLUORINATED POLYCYCLIC AROMATIC COMPOUNDS AND THE USE THEREOF AS ADDITIVE POLYCYCLIC AROMATIC COMPOUNDS | LUTHE GREGOR (DE) | 2001-04-26 | — | — | WO | disclosed |