Bicarbonate

Bicarbonate

SCHEMBL7558223

N.N.O=C(O)O.[NaH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28482715 1.00
Bicarbonate SCHEMBL2502923 1.00
Bicarbonate SCHEMBL10962541 1.00 CA1 (0.71)
Bicarbonate SCHEMBL28159606 0.94 CA1 (0.62)
Bicarbonate SCHEMBL29233812 0.94
Bicarbonate SCHEMBL27838189 0.94
Bicarbonate SCHEMBL29043772 0.94 CA1 (0.62)
Bicarbonate SCHEMBL29040289 0.94
Bicarbonate SCHEMBL6428174 0.94
Bicarbonate SCHEMBL28232617 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020006375-A1 Hydrotalcite compounds of low uranium (U) content and processes for their preparation KYOWA CHEMICAL INDUSTRY CO., LTD. 2002-01-17 US disclosed
US-6287532-B1 FROM WATER SOLUBLE ALUMINUM, MAGNESIUM AND ZINC COMPOUND; PRECIPITATION KYOWA CHEMICAL INDUSTRY CO LTD (JP) 2001-09-11 US disclosed