Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | GCGR | P47871 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152557 | 0.92 | HMGCR (0.66) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9743387 | 0.91 | HMGCR (0.64) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9743399 | 0.91 | HMGCR (0.64) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9270541 | 0.89 | HMGCR (0.62) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9270549 | 0.89 | HMGCR (0.62) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9270484 | 0.88 | HMGCR (0.61) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| Cerivastatin SCHEMBL5508956 | 0.87 | HMGCR (1.00) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| Cerivastatin SCHEMBL10024041 | 0.87 | HMGCR (1.00) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| Cerivastatin SCHEMBL6241954 | 0.87 | HMGCR (1.00) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| Cerivastatin SCHEMBL6241950 | 0.87 | HMGCR (1.00) | HMGCRESR1CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |