SCHEMBL7558334

SCHEMBL7558334

O=C(OCc1cc(=O)c(O)co1)c1ccc(C(=O)OCc2cc(=O)c(O)co2)cc1

nearest known ligand 0.94

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.63
GAA P10253 1/20 0.63
DAO P14920 4/20 0.59
ELANE P08246 3/20 0.56
TYR P14679 3/20 0.56
KDM4E B2RXH2 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361178 0.97 POLB (0.61) POLBGAADAOELANETYR
SCHEMBL3220810 0.93 DAO (0.63) POLBGAADAOELANETYR
SCHEMBL361231 0.91 POLB (0.61) POLBGAADAOELANETYR
SCHEMBL28313263 0.91 POLB (0.64) POLBGAADAOELANETYR
SCHEMBL7550581 0.90 POLB (0.60) POLBGAADAOELANETYR
SCHEMBL360885 0.87 POLB (0.57) POLBGAADAOELANETYR
SCHEMBL7551138 0.86 POLB (0.53) POLBGAADAOELANETYR
SCHEMBL7554264 0.85 DAO (0.54) POLBGAADAOELANETYR
SCHEMBL9085769 0.82 SERPINE1 (0.56) DAOELANETYR
SCHEMBL361245 0.82 DAO (0.58) DAOELANETYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002053562-A1 KOJIC ACID DERIVATIVE AND PREPARATION METHOD THEREOF PACIFIC CORPORATION (KR) 2002-07-11 WO disclosed