Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769673 | 0.83 | TSHR (0.42) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL28206674 | 0.83 | TSHR (0.42) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL15744637 | 0.83 | TSHR (0.42) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL7558590 | 0.76 | TSHR (0.37) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL7558521 | 0.76 | TSHR (0.37) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL8074160 | 0.76 | CES1 (0.37) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL777643 | 0.75 | CA2 (0.52) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL21914595 | 0.75 | CA2 (0.35) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL7755415 | 0.74 | TSHR (0.35) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL29170929 | 0.74 | CA1 (0.50) | TSHRCYP3A4CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638112-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-0792255-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0792255-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015092-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |
| US-5482650-A | Liquid crystal compounds having perfluoroether terminal portions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |
| US-5437812-A | Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-01 | — | — | US | disclosed |
| US-5262082-A | Ferroelectric liquid crystal compounds having perfluoroether terminal portions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| WO-1993022396-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |