Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.46 |
| ▸ | RXRB | P28702 | 6/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | RARG | P13631 | 4/20 | 0.46 |
| ▸ | RARA | P10276 | 3/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473196 | 1.00 | RXRA (0.46) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7561601 | 0.93 | RXRA (0.41) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6473487 | 0.93 | RXRA (0.41) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6473035 | 0.91 | RXRA (0.38) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7560526 | 0.91 | RXRA (0.38) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7559742 | 0.89 | RXRA (0.56) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6473429 | 0.89 | RXRA (0.56) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7560511 | 0.87 | RARG (0.41) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6478155 | 0.87 | RARG (0.41) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7562918 | 0.87 | RXRA (0.39) | RXRARXRBRXRGRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |