Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR1D | P28221 | 5/20 | 0.41 |
| ▸ | HTR1B | P28222 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723092 | 0.91 | CNR2 (0.46) | CNR2HTR1AHTR1DHTR1BMAPT | |
| SCHEMBL7557837 | 0.85 | RARB (0.45) | HTR1AHTR1DHTR1BMAPTTDP1 | |
| SCHEMBL7561859 | 0.84 | CNR2 (0.36) | CNR2MAPTTDP1TP53CYP3A4 | |
| SCHEMBL9494273 | 0.84 | RARB (0.47) | CNR2TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7920156 | 0.81 | MEN1 (0.43) | MAPTMAPK1TP53CYP3A4MEN1 | |
| SCHEMBL27509805 | 0.78 | CNR2 (0.49) | CNR2HTR1AHTR1DHTR1BMAPT | |
| SCHEMBL8903027 | 0.78 | CNR2 (0.49) | CNR2HTR1AHTR1DHTR1BMAPT | |
| SCHEMBL27510517 | 0.78 | CNR2 (0.49) | CNR2HTR1AHTR1DHTR1BMAPT | |
| SCHEMBL27509452 | 0.78 | CNR2 (0.49) | CNR2HTR1AHTR1DHTR1BMAPT | |
| SCHEMBL27524429 | 0.78 | CNR2 (0.49) | CNR2HTR1AHTR1DHTR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944565-B1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-07-31 | — | — | EP | disclosed |