Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722885 | 0.91 | MEN1 (0.43) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8038196 | 0.89 | RARB (0.47) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7928543 | 0.85 | DHODH (0.38) | MEN1USP2ALDH1A1CYP3A4KMT2A | |
| SCHEMBL14526059 | 0.82 | GCGR (0.45) | RARBRARARARG | |
| SCHEMBL7558756 | 0.81 | CNR2 (0.46) | MEN1CYP3A4MAPK1KMT2AMAPT | |
| SCHEMBL7925854 | 0.79 | MEN1 (0.35) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7558492 | 0.79 | MAPK1 (0.43) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL15362600 | 0.78 | CYP3A4 (0.42) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL15625646 | 0.78 | CYP3A4 (0.42) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7557453 | 0.77 | RARB (0.46) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946474-B1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0946474-A1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027037-A1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |