Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL27955723 | 1.00 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Aspartic Acid SCHEMBL8919110 | 1.00 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Ornithine Aketoglutarate SCHEMBL361184 | 1.00 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Aspartic Acid SCHEMBL28321586 | 1.00 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Ornithine SCHEMBL361185 | 1.00 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Aspartic Acid SCHEMBL14656074 | 0.98 | GSR (0.67) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Aspartic Acid SCHEMBL27858630 | 0.98 | GSR (0.67) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Ornithine SCHEMBL14656075 | 0.98 | GSR (0.67) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1425215 | 0.94 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1425217 | 0.94 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119804682-A | Analysis method for detecting related substances in ornithine aspartate | 远大医药（中国）有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119413935-A | Method for detecting ornithine aspartate isomer | 远大医药（中国）有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118415276-A | Application of ornithine aspartate as feed additive in animal feed | 安徽万合佳尔生物科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117434176-A | Method for separating and measuring isomer in ornithine aspartate | 北京尚修堂医药科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114965746-B | Ornithine aspartate injection impurity analysis and detection method | 扬子江药业集团广州海瑞药业有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-113336663-B | Method for preparing ornithine aspartate by using ornithine catalytic liquid | 无锡晶海氨基酸股份有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116549597-A | Anti-alcohol liver-protecting composition | 广东长兴生物科技股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116413341-A | Analysis method for detecting ornithine aspartate impurities | 武汉瑞晟药业有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-116370601-A | Preparation method of ornithine aspartate injection | 武汉瑞晟药业有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-115397263-B | Composition containing N-acetylglucosamine and preparation method and application thereof | 张曼 | 2023-04-14 | — | — | CN | claimed |
| CN-101961315-A | Ornithine aspartate liposome injection | HAINAN MEILAN SMITH KLINE PHARMACEUTICAL CO LTD | 2011-02-02 | — | — | CN | claimed |
| CN-101880240-A | Ornithine and aspartate compound and novel method thereof | MING WANG | 2010-11-10 | — | — | CN | claimed |
| CN-101843587-A | Preparation method of ornithine aspartate powder injection for injection | HUBEI HOPE PHARMACEUTICAL CO LTD | 2010-09-29 | — | — | CN | claimed |
| EP-2219642-A1 | SILIBININ COMPONENT FOR THE TREATMENT OF HEPATITIS | Madaus GmbH (DE) | 2010-08-25 | — | — | EP | claimed |
| WO-2009062737-A1 | SILIBININ COMPONENT FOR THE TREATMENT OF HEPATITIS | MADAUS GMBH (DE) | 2009-05-22 | — | — | WO | claimed |
| EP-1044672-B1 | Water-in-oil emulsified cosmetic | SHISEIDO CO LTD (JP) | 2007-03-07 | — | — | EP | claimed |
| CN-1679941-A | Compound preparation consisting of taurine and medicines for hepatopathy and production thereof | FUKANGREN BIO PHARMACEUTICAL S (CN) | 2005-10-12 | — | — | CN | claimed |
| EP-0477991-B1 | Process for producing crystals of salt of acidic amino acid and basic amino acid | KYOWA HAKKO KOGYO KK (JP) | 1994-12-28 | — | — | EP | claimed |
| US-5227007-A | PROCESS FOR PRODUCING CRYSTALS OF SALT OF ACIDIC AMINO ACID AND BASIC AMINO ACID | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-07-13 | — | — | US | claimed |
| EP-0477991-A1 | Process for producing crystals of salt of acidic amino acid and basic amino acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-04-01 | — | — | EP | claimed |