⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179793 | 0.81 | — | — | |
| SCHEMBL7872339 | 0.79 | — | — | |
| SCHEMBL654896 | 0.77 | CA5A (0.36) | — | |
| SCHEMBL28624 | 0.75 | — | — | |
| SCHEMBL8039427 | 0.74 | CA5A (0.33) | — | |
| SCHEMBL8039428 | 0.74 | CA5A (0.33) | — | |
| Ethylene SCHEMBL28985424 | 0.74 | CA5A (0.33) | — | |
| SCHEMBL7777190 | 0.74 | CA5A (0.33) | — | |
| SCHEMBL8775077 | 0.74 | CA5A (0.33) | — | |
| SCHEMBL1030926 | 0.74 | CA5A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104327084-B | The small molecule myristate inhibitors and its application method of BCR ABL | 达那-法伯癌症研究所 | 2017-06-06 | — | — | CN | disclosed |
| CN-104311563-B | The small molecule myristate inhibitors of BCR-ABL and using method thereof | 达那-法伯癌症研究所 | 2016-12-07 | — | — | CN | disclosed |
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104327084-A | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA FARBER CANCER INST INC | 2015-02-04 | — | — | CN | disclosed |
| CN-104311563-A | Small molecule myristate inhibitors of BCR-ABL and methods of use | DANA FARBER CANCER INST INC | 2015-01-28 | — | — | CN | disclosed |
| CN-104193725-A | ORGANIC COMPOUNDS | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| CN-101917849-B | small molecule myristate inhibitors of BCR-ABL and methods of use thereof | DANA FARBER CANCER INST INC | 2014-11-05 | — | — | CN | disclosed |
| CN-102076665-B | Organic compounds | NOVARTIS AG | 2014-09-03 | — | — | CN | disclosed |
| EP-1223152-A2 | Decomposition method of hydrophilic polymer | Showa Denko K.K. (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0562476-B1 | Method for preparing a silver halide photographic emulsion | FUJI PHOTO FILM CO LTD (JP) | 2000-10-04 | — | — | EP | disclosed |
| US-5418124-A | Silver halide photographic emulsion and a photographic light-sensitive material | FUJI PHOTO FILM CO. LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5405737-A | Silver halide color photographic light-sensitive material comprising blue sensitive emulsion layers containing acylacetoamide type yellow dye forming couplers and reduction sensitized silver halide emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| US-5380631-A | Sharpness, stability, development inhibitor | FUJI PHOTO FILM CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5298570-A | Main chain of oligomer crosslinked with alkyhyroxyester,alkyl di/tri esters, acid, metal/ammmonium or amine salt of acid | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0562476-A1 | A silver halide photographic emulsion and a photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0551130-A1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-07-14 | — | — | EP | disclosed |
| EP-0291590-B1 | CEMENT DISPERSANT | NIPPON SHOKUBAI CO., LTD. (JP) | 1992-09-30 | — | — | EP | disclosed |
| US-5137945-A | Dispersants | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4870120-A | ADDITION POLYMER HAVING SULFONIC ACID-CONTAINING MONOMER | NIPPON SHOKUBAI KAGAKU CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0291590-A1 | Cement dispersant | NIPPON SHOKUBAI CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |