SCHEMBL7559386

SCHEMBL7559386

C=CCc1ccc(-c2cnc(-c3ccc(C=CCCCC(C)F)cc3)cn2)cc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
MITF O75030 1/20 0.34
KLF5 Q13887 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559382 1.00 KDM4E (0.35) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7557947 0.93 RAB9A (0.37) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7557944 0.93 RAB9A (0.37) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7556620 0.92 RAB9A (0.38) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7551691 0.92 RAB9A (0.38) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7556619 0.92 RAB9A (0.38) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7551688 0.92 RAB9A (0.38) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7555515 0.92 RAB9A (0.41) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7555509 0.92 RAB9A (0.41) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL7551159 0.92 RAB9A (0.36) KDM4EALDH1A1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-B1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2002-01-09 EP disclosed
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed