Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559477 | 1.00 | KDM4D (0.31) | KDM4DHDAC3HDAC1HDAC2TNF | |
| SCHEMBL4526115 | 0.85 | USP30 (0.33) | KDM4DTNFIRAK4BRD4 | |
| SCHEMBL4526111 | 0.85 | USP30 (0.33) | KDM4DTNFIRAK4BRD4 | |
| SCHEMBL7512228 | 0.85 | KDM4D (0.33) | KDM4DHDAC3HDAC1HDAC2TNF | |
| SCHEMBL7559233 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL7513387 | 0.81 | PIM1 (0.39) | KDM4DHDAC3HDAC1HDAC2 | |
| SCHEMBL7558234 | 0.80 | HCRTR2 (0.32) | — | |
| SCHEMBL7513215 | 0.78 | ACACB (0.40) | — | |
| SCHEMBL4501896 | 0.78 | ROCK2 (0.44) | IRAK4 | |
| SCHEMBL7511353 | 0.78 | AAK1 (0.36) | KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |