Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552728 | 1.00 | HPGD (0.46) | HPGDMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL7553674 | 0.95 | MEN1 (0.46) | HPGDMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL7552498 | 0.95 | MEN1 (0.46) | HPGDMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL7557779 | 0.80 | CNR2 (0.57) | HPGDMEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL7552633 | 0.77 | SMN1; SMN2 (0.56) | HPGDMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL4467676 | 0.76 | HPGD (0.53) | HPGDMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL15904166 | 0.74 | ALDH1A1 (0.52) | HPGDMEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL7560193 | 0.74 | ESR1 (0.40) | HDAC1HDAC8HDAC2 | |
| SCHEMBL7553069 | 0.74 | ESR1 (0.40) | HDAC1HDAC8HDAC2 | |
| SCHEMBL7555090 | 0.74 | ESR1 (0.40) | HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |