Methane

Methane

SCHEMBL7559602

C.Cc1oc(-c2ccccc2)nc1COc1ccc2cc(O)ccc2c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.67
FFAR1 O14842 1/20 0.61
PPARG P37231 11/20 0.56
PPARA Q07869 11/20 0.56
MAPT P10636 4/20 0.52
KDM4E B2RXH2 1/20 0.51
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4030957 0.90 FFAR1 (0.70) KDRFFAR1PPARGPPARAMAPT
SCHEMBL3528719 0.89 KDR (0.76) KDRFFAR1PPARGPPARAMAPT
SCHEMBL7559600 0.85 KDR (0.83) KDRFFAR1PPARGPPARAMAPT
SCHEMBL7564833 0.83 KDR (0.65) KDRFFAR1PPARGPPARAMAPT
SCHEMBL19392906 0.83 FFAR1 (0.68) KDRFFAR1PPARGPPARAMAPT
SCHEMBL9092871 0.82 KDR (0.64) KDRFFAR1PPARGPPARAMAPT
SCHEMBL7563293 0.82 KDR (0.60) KDRFFAR1PPARGPPARAMAPT
SCHEMBL4032011 0.82 FFAR1 (0.70) KDRFFAR1PPARGPPARAMAPT
SCHEMBL8128837 0.82 KDR (0.66) KDRFFAR1PPARGPPARAMAPT
SCHEMBL6248263 0.81 KDR (0.63) KDRFFAR1PPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1229026-A1 ALKOXYIMINOALKANOIC ACID DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2002-08-07 EP disclosed