Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | PPARA | Q07869 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372016 | 0.85 | FFAR1 (0.65) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL9721982 | 0.84 | KDR (0.71) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL19392906 | 0.82 | FFAR1 (0.68) | KDRFFAR1PPARGPPARAMAPT | |
| Methane SCHEMBL7559602 | 0.81 | KDR (0.67) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL4032011 | 0.81 | FFAR1 (0.70) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL4030957 | 0.81 | FFAR1 (0.70) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL6245582 | 0.81 | KDR (0.57) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL6963034 | 0.81 | KDR (0.57) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL5802990 | 0.80 | KDR (0.72) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL3528719 | 0.80 | KDR (0.76) | KDRFFAR1PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597257-A1 | OXAZOLE-DERIVATIVES AS PPAR AGONISTS | PFIZER INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | AGOURON PHARMACEUTICALS, INC. | 2004-10-21 | — | — | US | disclosed |
| WO-2004074284-A1 | OXAZOLE-DERIVATIVES AS PPAR AGONISTS | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | PPARG, PPARA, PPARD | KDR 1033/4885FFAR1 5/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.