Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | YARS1 | P54577 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753174 | 0.91 | SLC7A5 (0.63) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL20865641 | 0.89 | HDAC8 (0.64) | HDAC8SLC7A5KDM4E | |
| Hydrochloric Acid SCHEMBL20854816 | 0.87 | HDAC8 (0.67) | HDAC8SLC7A5KDM4E | |
| SCHEMBL24277516 | 0.85 | HDAC8 (0.61) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL29520758 | 0.85 | HDAC8 (0.61) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL24277517 | 0.85 | HDAC8 (0.61) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL15399610 | 0.85 | HDAC8 (0.61) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL3690574 | 0.83 | HDAC8 (0.60) | HDAC8SLC7A5KDM4EPTGS1HIF1A | |
| SCHEMBL29220965 | 0.83 | HDAC8 (0.59) | HDAC8SLC7A5KDM4ECA1CA2 | |
| SCHEMBL26980197 | 0.83 | HDAC8 (0.60) | HDAC8SLC7A5KDM4EPTGS1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |
| US-4033997-A | Preparation of dopamine derivatives | ABBOTT LABORATORIES (US) | 1977-07-05 | — | — | US | disclosed |