Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | CDC25B | P30305 | 4/20 | 0.47 |
| ▸ | ACP1 | P24666 | 3/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | TST | Q16762 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775172 | 0.84 | CES2 (0.54) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL8775161 | 0.84 | CES2 (0.54) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL6934073 | 0.84 | CES2 (0.54) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL8775369 | 0.84 | CES2 (0.54) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL8775076 | 0.84 | CES2 (0.54) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL8116635 | 0.82 | CES2 (0.51) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL8482591 | 0.81 | CES2 (0.36) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL4574953 | 0.81 | ABHD16A (0.40) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL3104384 | 0.80 | CES2 (0.45) | CES2ABHD16APTPN1CDC25BACP1 | |
| SCHEMBL18784042 | 0.80 | ABHD16A (0.48) | CES2ABHD16APTPN1CDC25BACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223168-A1 | Method for the preparation of enantiomerically enriched amino and hydroxyfuranones | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2002-07-17 | — | — | EP | disclosed |