SCHEMBL7559992

SCHEMBL7559992

CCC(CO)(CO)CO[N+](=O)[O-]

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL6271440 0.96 ALDH1A1 (0.56) ALDH1A1LMNA
SCHEMBL17482168 0.96 ALDH1A1 (0.60) ALDH1A1LMNA
Propatyl Nitrate SCHEMBL214199 0.87 ALDH1A1 (0.71) ALDH1A1
SCHEMBL8277378 0.87 ALDH1A1 (0.71) ALDH1A1
SCHEMBL12168234 0.87 ALDH1A1 (0.71) ALDH1A1
Pentrinitrol SCHEMBL122322 0.87 ALDH1A1 (0.71) ALDH1A1LMNA
Pentaerythrityl Dinitrate SCHEMBL2290461 0.87 ALDH1A1 (0.71) ALDH1A1LMNA
Pentrinitrol SCHEMBL15777772 0.87 ALDH1A1 (0.71) ALDH1A1LMNA
Pentaerythrityl Mononitrate SCHEMBL2293171 0.87 ALDH1A1 (0.71) ALDH1A1LMNA
Pentaerythritol Tetranitrate SCHEMBL15543872 0.85 ALDH1A1 (0.76) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0904110-B1 NITRIC OXIDE DONORS CAPABLE OF REDUCING TOXICITY FROM DRUGS NICOX SA (FR) 2002-07-24 EP claimed
CN-109810092-B Cyclic carbonate monomer containing nitric oxide donor, preparation and application thereof 中国药科大学 2021-03-19 CN disclosed