Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273440 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL2495325 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL5171234 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL1617171 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL261179 | 0.77 | CHRNA7 (0.50) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL260527 | 0.77 | CHRNA7 (0.50) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL8236713 | 0.77 | CHRM2 (0.52) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL5167294 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL5108694 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAACHRNA7CHRM2CHRM1 | |
| SCHEMBL260902 | 0.77 | CHRNA7 (0.50) | ALDH1A1GAACHRNA7CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009284-A1 | 2,6-METHANO-2H-1-BENZOXOCINCARBOXAMIDES AS 5-HT3-ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-06-11 | — | — | WO | disclosed |