SCHEMBL7560056

SCHEMBL7560056

CC(C)(C)N1C(=O)C(Cl)=C(Cl)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.48
WRN Q14191 1/20 0.48
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
CES2 O00748 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
BCHE P06276 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
CES1 P23141 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051423 0.83 BLM (0.35) BLMWRNCA12CA1CA9
SCHEMBL1298228 0.81 BLM (0.34) BLMWRN
SCHEMBL14447509 0.72 RAB9A (0.40) CA12CA1CA9MEN1ALDH1A1
SCHEMBL16980269 0.71
SCHEMBL26864511 0.69
SCHEMBL17789602 0.67 NPC1 (0.30) BLMWRN
SCHEMBL19420630 0.67 MEN1 (0.30) BLMMEN1ALDH1A1TP53CYP3A4
SCHEMBL24145125 0.65
SCHEMBL21017060 0.65
SCHEMBL12737780 0.65 RAB9A (0.42) CA12CA1CA9KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-0877061-A1 TRIPHENYLBORANE-ROSIN AMINE ADDUCT AND USE OF THE SAME Yoshitomi Fine Chemicals, Ltd. (JP) 1998-11-11 EP disclosed