Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | SQLE | Q14534 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562570 | 0.91 | KMT2A (0.64) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL7589662 | 0.91 | KMT2A (0.64) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL7589665 | 0.91 | KMT2A (0.64) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL7562565 | 0.91 | KMT2A (0.64) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL11295324 | 0.83 | SQLE (0.56) | TSHRKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL15709505 | 0.80 | TSHR (0.54) | TSHRKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL15902956 | 0.79 | SQLE (0.59) | TSHRKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL9579346 | 0.78 | TSHR (0.52) | TSHRKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL1191493 | 0.78 | TSHR (0.52) | TSHRKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL20633519 | 0.76 | TSHR (0.50) | TSHRKMT2AMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |
| US-5231232-A | Method of preparing C-18 ketones used in the manufacture of Vitamins E and K | LOYOLA UNIVERSITY OF CHICAGO (US) | 1993-07-27 | — | — | US | disclosed |