Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.63 |
| ▸ | SQLE | Q14534 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589665 | 1.00 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL7589662 | 1.00 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL7562570 | 1.00 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL7560079 | 0.91 | TSHR (0.54) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL9474487 | 0.86 | SQLE (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL9474498 | 0.86 | SQLE (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL28588501 | 0.83 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL29462483 | 0.83 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL83307 | 0.83 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL160736 | 0.83 | KMT2A (0.64) | KMT2AALOX15MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047910-B | Aromatic farnesyl compound and application thereof | 杭州百诚医药科技股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-112047910-A | Aromatic farnesyl compound and application thereof | 杭州百诚医药科技股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-107519160-B | Application of hydroquinone farnesyl compound | 杭州百诚医药科技股份有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-107106537-B | Aromatic farnesyl compound and application thereof | 杭州百诚医药科技股份有限公司 | 2020-07-17 | — | — | CN | disclosed |
| US-10441562-B2 | Aromatic farnesyl compound and application thereof | INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2019-10-15 | — | — | US | disclosed |
| US-20170224651-A1 | AROMATIC FARNESYL COMPOUND AND APPLICATION THEREOF | INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-08-10 | — | — | US | disclosed |
| WO-2016173274-A1 | AROMATIC FARNESYL COMPOUND AND APPLICATION THEREOF | 中国科学院微生物研究所 | 2016-11-03 | — | — | WO | disclosed |
| EP-1013652-B1 | Process for preparation of substituted chromanderivatives | BASF AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-1013652-A2 | Process for preparation of substituted chromanderivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10441562-B2 | Aromatic farnesyl compound and application thereof | HMGCR, PYGL, TGFB1 | KMT2A 3950/4885ALOX15 2028/4885MAPT 2609/4885 |
| US-20170224651-A1 | AROMATIC FARNESYL COMPOUND AND APPLICATION THEREOF | HMGCR, PYGL, TGFB1 | KMT2A 3950/4885ALOX15 2028/4885MAPT 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.