Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510704 | 0.88 | TYR (0.51) | LGALS3 | |
| SCHEMBL29161024 | 0.83 | TYR (0.61) | — | |
| SCHEMBL467820 | 0.83 | TYR (0.61) | — | |
| SCHEMBL15711517 | 0.83 | TYR (0.61) | — | |
| SCHEMBL29220897 | 0.82 | LGALS3 (0.61) | LGALS3NT5ELGALS4PTPN2PTPN1 | |
| SCHEMBL2455542 | 0.82 | PTPN2 (0.49) | ALDH1A1NT5EPTPN2PTPN1 | |
| SCHEMBL2454672 | 0.82 | PTPN2 (0.49) | ALDH1A1NT5EPTPN2PTPN1 | |
| SCHEMBL7544589 | 0.82 | CYP1A2 (0.48) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| SCHEMBL7938131 | 0.82 | MAOB (0.46) | LGALS3 | |
| SCHEMBL9236676 | 0.82 | LGALS3 (0.62) | LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169327-A1 | L-ARABINO-DISACCHARIDES OF ANTHRACYCLINES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000053615-A1 | L-ARABINO-DISACCHARIDES OF ANTHRACYCLINES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |