Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 10/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560445 | 1.00 | MEN1 (0.43) | MEN1KMT2ASLC6A3KDM4CREN | |
| SCHEMBL7540005 | 0.92 | MEN1 (0.43) | MEN1KMT2ASLC6A3KDM4CREN | |
| SCHEMBL6043272 | 0.83 | REN (0.51) | MEN1KMT2AREN | |
| SCHEMBL6043267 | 0.83 | REN (0.51) | MEN1KMT2AREN | |
| SCHEMBL7560322 | 0.82 | REN (0.39) | SLC6A3REN | |
| SCHEMBL6042754 | 0.80 | MEN1 (0.42) | MEN1KMT2AKDM4CRENNPC1 | |
| SCHEMBL6042749 | 0.80 | MEN1 (0.42) | MEN1KMT2AKDM4CRENNPC1 | |
| SCHEMBL7562108 | 0.79 | SLC6A4 (0.39) | SLC6A3RENRAB9A | |
| SCHEMBL7569293 | 0.79 | TACR1 (0.41) | SLC6A3 | |
| SCHEMBL7561346 | 0.78 | SLC6A4 (0.38) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |