Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.56 |
| ▸ | PDE4A | P27815 | 4/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808190 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL70835 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL4637156 | 0.98 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL6883557 | 0.98 | ALDH1A1 (0.66) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL2840516 | 0.94 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL22713946 | 0.94 | ALDH1A1 (0.68) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL2847455 | 0.92 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL27512098 | 0.91 | PDE4B (0.59) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL8845986 | 0.90 | PDE4B (0.49) | ALDH1A1TSHRPDE4BPDE3APDE4D | |
| SCHEMBL5905463 | 0.89 | PDE4B (0.48) | ALDH1A1TSHRPDE4BPDE3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015044-A1 | N-BENZYLOXAMIC ACID, OXAMATE, AND OXAMIDE DERIVATIVES AND THEIR USE AS TNF AND PDE IV INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-05 | — | — | WO | disclosed |