SCHEMBL7560864

SCHEMBL7560864

COc1ccc(Oc2ccc(OC)cc2OC)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.74
CA1 P00915 2/20 0.74
CA2 P00918 2/20 0.74
CA7 P43166 2/20 0.74
CA9 Q16790 2/20 0.74
CA14 Q9ULX7 2/20 0.74
ALDH1A1 P00352 5/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MAPK1 P28482 1/20 0.58
HTT P42858 1/20 0.58
CYP1A1 P04798 5/20 0.52
CYP1A2 P05177 5/20 0.52
CYP1B1 Q16678 5/20 0.52
CYP3A4 P08684 1/20 0.52
MEN1 O00255 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
KMT2A Q03164 1/20 0.52
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7455927 0.93 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL27492322 0.91 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL9941710 0.91 CA12 (0.81) CA12CA1CA2CA7CA9
SCHEMBL11784875 0.90 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL2752533 0.86 CA12 (0.61) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL481491 0.85 CA12 (1.00) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL29350371 0.85 CA12 (1.00) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL27777905 0.85 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL12770839 0.85 AR (0.59) CA12CA1CA2CA7CA9
SCHEMBL11401708 0.84 MAPK1 (0.56) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1001312-B1 Radiation sensitive recording material for the production of dry offset printing plates AGFA GEVAERT (BE) 2002-07-31 EP disclosed
EP-1001312-A1 Radiation sensitive recording material for the production of dry offset printing plates Agfa-Gevaert AG (DE) 2000-05-17 EP disclosed