SCHEMBL11784875

SCHEMBL11784875

COc1ccc(Oc2ccccc2)c(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA7 P43166 1/20 0.65
CA9 Q16790 1/20 0.65
CA14 Q9ULX7 1/20 0.65
ALDH1A1 P00352 1/20 0.63
MAPK1 P28482 1/20 0.63
HTT P42858 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
TTR P02766 3/20 0.62
LTA4H P09960 1/20 0.59
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
LMNA P02545 1/20 0.51
ALOX12 P18054 1/20 0.51
CYP1A1 P04798 3/20 0.50
CYP1A2 P05177 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11015595 0.92 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL7560864 0.90 CA12 (0.74) CA12CA1CA2CA7CA9
Nitrogen SCHEMBL11336114 0.89 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL11646840 0.86 LTA4H (0.61) CA12CA1CA2CA7CA9
SCHEMBL9941710 0.85 CA12 (0.81) CA12CA1CA2CA7CA9
SCHEMBL2099937 0.84 ALDH1A1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL7455927 0.83 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL17912857 0.83 CYP1A2 (0.57) CA12CA1CA2CA7CA9
SCHEMBL17912814 0.83 CYP1A2 (0.57) CA12CA1CA2CA7CA9
SCHEMBL7038743 0.82 LTA4H (0.57) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447441-A Difluoromethyl reagent and preparation method and application thereof 深圳大学 2024-01-26 CN claimed
US-3963753-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed