⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17729851 | 1.00 | — | — | |
| SCHEMBL1945972 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL10623098 | 0.70 | — | — | |
| SCHEMBL2001030 | 0.70 | ALDH1A1 (0.46) | — | |
| SCHEMBL212538 | 0.70 | — | — | |
| SCHEMBL10463 | 0.67 | — | — | |
| SCHEMBL17729837 | 0.67 | — | — | |
| SCHEMBL27598855 | 0.65 | — | — | |
| SCHEMBL369996 | 0.64 | — | — | |
| SCHEMBL1760668 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247387-A1 | UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF | NORTHEASTERN UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
| US-9122151-B2 | Resist composition, resist film therefrom and method of forming negative pattern using the composition | FUJIFILM CORPORATION (JP) | 2015-09-01 | — | — | US | disclosed |
| US-8642824-B2 | Chemical methods for treating a metathesis feedstock | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-8329905-B2 | Synthesis of diethyl{[5-(3-fluorophenyl)-pyridine-2yl]methyl}phosphonate | MERCK SHARP & DOHME CORP. (US) | 2012-12-11 | — | — | US | disclosed |
| US-8258319-B2 | Exo- and diastereo- selective synthesis of himbacine analogs | SCHERING CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120219891-A1 | RESIST COMPOSITION, RESIST FILM THEREFROM AND METHOD OF FORMING NEGATIVE PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20110313180-A1 | THERMAL METHODS FOR TREATING A METATHESIS FEEDSTOCK | WILMAR TRADING PTE LTD (SG) | 2011-12-22 | — | — | US | disclosed |
| US-20110251392-A1 | EXO- AND DIASTEREO- SELECTIVE SYNTHESIS OF HIMBACINE ANALOGS | TOPROL ACQUISITION LLC | 2011-10-13 | — | — | US | disclosed |
| US-20110160472-A1 | CHEMICAL METHODS FOR TREATING A METATHESIS FEEDSTOCK | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100137597-A1 | SYNTHESIS Of DIETHYLPHOSPHONATE | SCHERING CORPORATION | 2010-06-03 | — | — | US | disclosed |
| US-20090281321-A1 | EXO- AND DIASTEREO- SELECTIVE SYNTHESES OF HIMBACINE ANALOGS | SCHERING CORPORATION | 2009-11-12 | — | — | US | disclosed |
| US-7365061-B2 | 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2002068883-A1 | CRYOGENIC REFRIGERATION SYSTEM USING MAGNETIC REFRIGERATOR FORECOOLING | PRAXAIR TECHNOLOGY, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| US-6415611-B1 | Cryogenic refrigeration system using magnetic refrigerator forecooling | PRAXAIR TECHNOLOGY, INC. | 2002-07-09 | — | — | US | disclosed |