Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041826 | 0.92 | REN (0.48) | REN | |
| SCHEMBL6041348 | 0.87 | REN (0.61) | REN | |
| SCHEMBL6042185 | 0.87 | REN (0.48) | REN | |
| SCHEMBL7084284 | 0.85 | REN (0.44) | RENPTGS2 | |
| SCHEMBL6042841 | 0.84 | REN (0.48) | REN | |
| SCHEMBL6041850 | 0.83 | REN (0.49) | REN | |
| SCHEMBL6041882 | 0.83 | REN (0.61) | REN | |
| SCHEMBL6041852 | 0.83 | REN (0.50) | REN | |
| SCHEMBL6042730 | 0.83 | REN (0.55) | REN | |
| SCHEMBL6043544 | 0.82 | REN (0.59) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-6150526-A | Piperidine derivative having renin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-6051712-A | PREVENTION OF HIGH BLOOD PRESSURE AND CARDIAC INSUFFICIENCY, AS WELL AS GLAUCOMA, CARDIAC INFARCT, KIDNEY INSUFFICIENCY AND RESTENOSIS | HOFFMANN-LA ROCHE INC. (US) | 2000-04-18 | — | — | US | disclosed |