SCHEMBL7561622

SCHEMBL7561622

C=C(C)C(=O)OCCOc1ccc(N=Nc2ccc(C#N)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
PPARA Q07869 5/20 0.54
PPARD Q03181 4/20 0.54
POLB P06746 1/20 0.49
APEX1 P27695 1/20 0.49
HTT P42858 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MMP2 P08253 5/20 0.45
MMP3 P08254 4/20 0.45
MMP1 P03956 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
PPARG P37231 2/20 0.39
HRH2 P25021 1/20 0.38
HRH1 P35367 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004246 1.00 ALDH1A1 (0.55) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL14791140 0.96 ALDH1A1 (0.51) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL14597114 0.91 MAPT (0.52) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL20828630 0.91 POLB (0.57) PPARAPPARDPOLBAPEX1HTT
SCHEMBL8819098 0.88 MAPT (0.49) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL7578689 0.88 MAPT (0.58) ALDH1A1MAPTPOLBAPEX1HTT
SCHEMBL12676171 0.87 POLB (0.44) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL5848329 0.86 PPARD (0.41) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL5705387 0.86 PPARD (0.41) ALDH1A1MAPTPPARAPPARDPOLB
SCHEMBL10050683 0.86 MAPT (0.63) ALDH1A1MAPTPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-20130070899-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed
EP-0622789-B1 Sheet-like structures containing side chain polymers BAYER AG (DE) 2002-08-07 EP disclosed
US-5543267-A Photo-induced optically anisotropic amorphous film materials from side group polymers AGFA-GEVAERT AG (DE) 1996-08-06 US disclosed
EP-0622789-A1 Sheet-like structures containing side chain polymers Agfa-Gevaert AG (DE) 1994-11-02 EP disclosed