SCHEMBL7561849

SCHEMBL7561849

CC(C)C1CCCCC1(N)N.Nc1ccc2ccccc2c1N

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 7/20 0.38
SLC6A3 Q01959 7/20 0.38
SLC6A2 P23975 5/20 0.38
METAP2 P50579 1/20 0.32
METAP1 P53582 1/20 0.32
CYP2D6 P10635 1/20 0.32
BCHE P06276 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7563948 0.74
SCHEMBL31390038 0.71 ALDH1A1 (0.56) SLC6A2KDM4EALDH1A1MAPTHPGD
SCHEMBL64806 0.71 ALDH1A1 (0.56) SLC6A2KDM4EALDH1A1MAPTHPGD
Hydrazine SCHEMBL28260617 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
SCHEMBL27653414 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
Hydrogen Sulfide SCHEMBL28320748 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL430346 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL1286518 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
Naphthalene SCHEMBL28349112 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD
SCHEMBL28259949 0.69 ALDH1A1 (0.54) SLC6A2KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179526-A2 Cyanoethylation of cycloaliphatic vicinal primary diamines AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-02-13 EP disclosed
US-6245932-B1 REACTING ACRYLONITRILE AND A DIAMINE IN THE PRESENCE OF WATER AS A CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2001-06-12 US disclosed