Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382637 | 0.83 | HCAR2 (0.57) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL28147354 | 0.83 | HCAR2 (0.66) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL337504 | 0.82 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL337503 | 0.82 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL357565 | 0.82 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL27659194 | 0.81 | HCAR2 (0.85) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL30999857 | 0.79 | HCAR2 (0.76) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL7618935 | 0.78 | HCAR2 (0.74) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL7617250 | 0.78 | HCAR2 (0.74) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL7617245 | 0.78 | HCAR2 (0.74) | HCAR2LMNAAKR1B10AKR1B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066417-A1 | METHOD FOR THE PRODUCTION OF THE ENANTIOMERS OF 2-SUBSTITUTED BETA AMINO ACIDS | CHIROBLOCK GMBH (DE) | 2002-08-29 | — | — | WO | claimed |
| CN-110551057-B | Chiral 3,3-disubstituted oxindole derivative and synthesis method and application thereof | 华东师范大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-110551057-A | Chiral 3, 3-disubstituted oxindole derivative and synthesis method and application thereof | UNIV EAST CHINA NORMAL | 2019-12-10 | — | — | CN | disclosed |
| CN-105461629-A | Preparation method of 3-fluoroalkyl-1H-pyrazole-4-formic ester | UNIV TIANJIN | 2016-04-06 | — | — | CN | disclosed |