SCHEMBL7562115

SCHEMBL7562115

N/C(=C\C(F)(F)F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7562119 1.00 LDHA (0.35) LDHALDHBACHE
SCHEMBL10822012 0.72 LDHA (0.35) LDHALDHBACHE
SCHEMBL10822011 0.72 LDHA (0.35) LDHALDHBACHE
SCHEMBL5892080 0.71
SCHEMBL3802048 0.67
SCHEMBL3802047 0.67
SCHEMBL410526 0.67
SCHEMBL322715 0.67 PTGS1 (0.34)
SCHEMBL209706 0.67 PTGS1 (0.34)
SCHEMBL410527 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028938-B1 PRODUCTION OF AMINOHALOGENCROTONATES SOLVAY FLUOR & DERIVATE (DE) 2002-07-31 EP disclosed
EP-1028938-A1 PRODUCTION OF AMINOHALOGENCROTONATES Solvay Fluor und Derivate GmbH (DE) 2000-08-23 EP disclosed
WO-1999024390-A1 PRODUCTION OF AMINOHALOGENCROTONATES SOLVAY FLUOR UND DERIVATE GMBH (DE) 1999-05-20 WO disclosed