Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755191 | 0.82 | — | — | |
| SCHEMBL755190 | 0.82 | CYP1A2 (0.33) | TP53 | |
| SCHEMBL757120 | 0.82 | MAP3K5 (0.41) | KDM4ETP53 | |
| SCHEMBL10410694 | 0.81 | MAP3K5 (0.38) | TP53 | |
| SCHEMBL754882 | 0.76 | ALDH1A1 (0.39) | KDM4ETP53 | |
| SCHEMBL179304 | 0.74 | HPGD (0.33) | KDM4E | |
| SCHEMBL7019371 | 0.72 | PDPK1 (0.36) | KDM4ETP53 | |
| Ammonia Solution, Strong SCHEMBL16871771 | 0.71 | PDPK1 (0.35) | KDM4E | |
| SCHEMBL1371017 | 0.69 | PDPK1 (0.31) | — | |
| SCHEMBL753115 | 0.69 | PDK2 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138195-B2 | Inhibitors of human phosphatidylinositol 3-kinase delta | ICOS CORPORATION (US) | 2012-03-20 | — | — | US | disclosed |