Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 5/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042403 | 0.86 | PTGER1 (0.37) | PTGER1 | |
| SCHEMBL6042169 | 0.86 | REN (0.38) | MEN1KMT2ATACR1PTGER1 | |
| SCHEMBL6041450 | 0.85 | TACR1 (0.36) | TACR1 | |
| SCHEMBL6042274 | 0.75 | REN (0.38) | MEN1KMT2ATACR1ALDH1A1 | |
| SCHEMBL6042567 | 0.69 | REN (0.38) | TACR1ALDH1A1PTGER1 | |
| SCHEMBL6042512 | 0.67 | REN (0.42) | MEN1KMT2A | |
| SCHEMBL7504338 | 0.67 | REN (0.37) | PTGER1 | |
| SCHEMBL27504637 | 0.67 | TACR1 (0.39) | TACR1 | |
| SCHEMBL6042327 | 0.67 | REN (0.58) | — | |
| SCHEMBL6041569 | 0.66 | REN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |