Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526996 | 0.84 | GCGR (0.56) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL8846697 | 0.75 | DHODH (0.40) | GCGRDHODH | |
| SCHEMBL9302519 | 0.72 | ADORA2A (0.43) | MAPK14ADORA2ASCN9AMEN1KMT2A | |
| SCHEMBL7592397 | 0.68 | ADORA2A (0.38) | GCGRADORA1MAPK14ADORA2AHTR2A | |
| SCHEMBL7559726 | 0.67 | DPP4 (0.40) | DPP4ADORA1ADORA2AHTR2AHTR2C | |
| SCHEMBL7720729 | 0.66 | GCGR (0.86) | GCGRHMGCRESR1CHRM1TBXA2R | |
| SCHEMBL8846284 | 0.66 | MAPT (0.43) | ADORA1ADORA2ASQORDHODHMEN1 | |
| SCHEMBL13115444 | 0.66 | MAPK14 (0.53) | GCGRMAPK14MEN1KMT2A | |
| SCHEMBL9302391 | 0.64 | APP (0.42) | DHODHMEN1KMT2A | |
| SCHEMBL8703691 | 0.64 | ACP1 (0.41) | ADORA2ADHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |