Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986476 | 0.81 | CYP1A2 (0.39) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6942078 | 0.80 | CYP1A2 (0.38) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| SCHEMBL6939396 | 0.80 | CYP1A2 (0.38) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| SCHEMBL7563517 | 0.79 | CYP1A2 (0.37) | F10PRSS1KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7071388 | 0.79 | CYP1A2 (0.37) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| SCHEMBL2998879 | 0.79 | CYP1A2 (0.36) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7561338 | 0.79 | CYP1A2 (0.37) | F10PRSS1KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7561554 | 0.78 | GRIA2 (0.38) | F10PRSS1DDR1CYP1A2CYP2D6 | |
| SCHEMBL6937674 | 0.76 | MAPT (0.37) | F10PRSS1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL6941228 | 0.76 | F10 (0.35) | F10PRSS1DDR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183519-A1 | Antithrombotic carboxylic acid amides | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-05 | — | — | US | claimed |
| US-20020183519-A1 | Antithrombotic carboxylic acid amides | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183519-A1 | Antithrombotic carboxylic acid amides | SERPINC1, TFPI, F2 | F10 33/4885PRSS1 1106/4885KDM4E 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.