SCHEMBL756278

SCHEMBL756278

COC(C)COCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
TSHR P16473 4/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
GLA P06280 1/20 0.32
TP53 P04637 2/20 0.30
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARG P37231 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7772975 0.93 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL995207 0.93 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL13211624 0.89 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL14153358 0.89 TSHR (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL12801953 0.89 TSHR (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL18597289 0.87 TSHR (0.62) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL14035124 0.86 TSHR (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3616575 0.85 TSHR (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL10193790 0.84 TSHR (0.68) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL40032 0.83 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212338-B2 Organosilicones THE PROCTER & GAMBLE COMPANY (US) 2015-12-15 US disclosed
US-8648022-B2 Lubricating oil for refrigerator and hydraulic fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US disclosed
US-20120052039-A1 Organosilicones THE PROCTER & GAMBLE COMPANY 2012-03-01 US disclosed
EP-2322592-A1 Lubricating oil for refrigerator and refrigerator fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-05-18 EP disclosed
EP-2314665-A2 Lubricating oil for refrigerator and refrigerator fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-04-27 EP disclosed
EP-2284249-A2 Lubricating oil for refrigerator and refrigerator fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-02-16 EP disclosed
EP-2277981-A2 Lubricating oil for refrigerator and refrigerator fluid composition for refrigerator using the same Idemitsu Kosan Co., Ltd. (JP) 2011-01-26 EP disclosed
US-20090186788-A1 LUBRICATING OIL FOR REFRIGERATOR AND HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2009-07-23 US disclosed
US-20040157753-A1 Lubricating oil for refrigerators and hydraulic fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2004-08-12 US disclosed
EP-1312663-A1 LUBRICATING OIL FOR REFRIGERATOR AND HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2003-05-21 EP disclosed
US-5928393-A ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES NIPPON OIL CO., LTD. (JP) 1999-07-27 US disclosed
US-5837016-A ETHERIFIED (POLY)OXYALKYLENE GLYCOL CONTAINING AN AMIDE GROUP; INTERNAL COMBUSTION ENGINE ANTIDEPOSIT AGENTS NIPPON OIL CO., LTD. (JP) 1998-11-17 US disclosed
US-5755833-A URETHANE COMPOUND; ANTIDEPOSIT, ANTISLUDGING AGENT; GASOLINE NIPPON OIL CO., LTD. (JP) 1998-05-26 US disclosed
EP-0819753-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1998-01-21 EP disclosed
EP-0801128-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1997-10-15 EP disclosed
EP-0723985-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1996-07-31 EP disclosed
US-5536881-A Lubricating oil for compression-type refrigerators and polyoxyalkylene glycol derivatives IDEMITSU KOSAN CO., LTD. (JP) 1996-07-16 US disclosed
US-5269955-A 1,1,1,2-tetrafluoroethylene refrigerant IDEMITSU KOSAN CO., LTD. (JP) 1993-12-14 US disclosed
EP-0397037-B1 Use of polyoxyalkylene glycol derivative in lubricating oil for compression-type refrigerators. IDEMITSU KOSAN CO (JP) 1993-11-03 EP disclosed
EP-0397037-A2 Use of polyoxyalkylene glycol derivative in lubricating oil for compression-type refrigerators. IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120052039-A1 Organosilicones NISCH, XRCC6, RAD50 ALDH1A1 2605/4885TSHR 4805/4885MAPK1 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.