⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701 | 0.96 | — | — | |
| SCHEMBL29158280 | 0.92 | — | — | |
| SCHEMBL20636749 | 0.92 | — | — | |
| SCHEMBL29158347 | 0.92 | — | — | |
| SCHEMBL23451711 | 0.92 | — | — | |
| SCHEMBL25279269 | 0.92 | — | — | |
| SCHEMBL29158472 | 0.92 | — | — | |
| SCHEMBL603698 | 0.76 | LMNA (0.43) | — | |
| SCHEMBL26304 | 0.74 | — | — | |
| SCHEMBL221838 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254080-B1 | MALONIC ACID DERIVATIVES AND METHODS FOR THEIR SYNTHESIS | ENIRICERCHE S.p.A. (IT) | 1993-03-17 | — | — | EP | claimed |
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |