Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628816 | 0.86 | CES1 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9571882 | 0.83 | ALOX5 (0.62) | FFAR1ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8867104 | 0.82 | HTT (0.59) | ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL1594428 | 0.79 | SRD5A2 (0.58) | SRD5A2NR3C1FFAR1LTA4HEPHX2 | |
| SCHEMBL3192546 | 0.79 | SRD5A2 (0.58) | SRD5A2NR3C1FFAR1LTA4HEPHX2 | |
| SCHEMBL28159713 | 0.79 | SRD5A2 (0.63) | SRD5A2NR3C1FFAR1LTA4HEPHX2 | |
| SCHEMBL850542 | 0.79 | SRD5A2 (0.62) | SRD5A2NR3C1FFAR1LTA4HEPHX2 | |
| SCHEMBL5953992 | 0.79 | SRD5A2 (0.54) | SRD5A2NR3C1FFAR1LTA4HEPHX2 | |
| SCHEMBL12259199 | 0.78 | FFAR1 (0.62) | SRD5A2FFAR1LTA4HEPHX2ALDH1A1 | |
| SCHEMBL1145770 | 0.78 | SRD5A2 (0.83) | SRD5A2NR3C1FFAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |