SCHEMBL7563209

SCHEMBL7563209

C=CCCc1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.56
IDO1 P14902 2/20 0.47
AOC3 Q16853 1/20 0.46
MPO P05164 3/20 0.41
MAOB P27338 3/20 0.39
DAO P14920 2/20 0.39
HPGD P15428 1/20 0.39
LMNA P02545 1/20 0.38
PARP15 Q460N3 1/20 0.38
PARP14 Q460N5 1/20 0.38
PARP10 Q53GL7 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063273 0.88 TAAR1 (0.52) TAAR1IDO1AOC3MPOMAOB
SCHEMBL8072160 0.86 TAAR1 (0.50) TAAR1IDO1AOC3MPOMAOB
SCHEMBL8072473 0.84 TAAR1 (0.48) TAAR1IDO1AOC3MPOHPGD
SCHEMBL8077496 0.84 TAAR1 (0.48) TAAR1IDO1AOC3MPOHPGD
SCHEMBL8072559 0.84 TAAR1 (0.48) TAAR1IDO1AOC3MPOHPGD
SCHEMBL8073017 0.84 TAAR1 (0.48) TAAR1IDO1AOC3MPOHPGD
SCHEMBL9419295 0.83 TAAR1 (0.38) TAAR1IDO1AOC3MPOHPGD
SCHEMBL29373563 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL12478612 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPOMAOB
SCHEMBL2556909 0.78 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306520-A1 THIOPHENE COMPOUND AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2024-01-17 EP disclosed
CN-107849072-A EP4 activator bisphosphonates of acid amides connection and application thereof 西蒙弗雷泽大学 2018-03-27 CN disclosed
EP-2968211-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME Bio-Pharm Solutions Co., Ltd. (KR) 2016-01-20 EP disclosed
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2014142519-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
EP-1732929-B1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL IND LTD (JP) 2010-10-20 EP disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP disclosed
CN-1176898-C Fluoro 4-alkene-benzoic acid and its derivative, nematic liquid crystal composition and liquid crystal display using this composition 大日本油墨化学工业株式会社 2004-11-24 CN disclosed
EP-0637580-B1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL CO (JP) 2002-08-14 EP disclosed
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
CN-1227838-A Fluoro 4-alkene-benzoic acid and its derivative, nematic liquid crystal composition and liquid crystal display using this composition DAINIPPON INK & CHEMICALS (JP) 1999-09-08 CN disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed