Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.89 |
| ▸ | RAB9A | P51151 | 8/20 | 0.89 |
| ▸ | MAPT | P10636 | 7/20 | 0.89 |
| ▸ | NPC1 | O15118 | 7/20 | 0.89 |
| ▸ | MEN1 | O00255 | 6/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.89 |
| ▸ | TP53 | P04637 | 6/20 | 0.89 |
| ▸ | HPGD | P15428 | 6/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.89 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.89 |
| ▸ | POLB | P06746 | 4/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.89 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.89 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.89 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.89 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.89 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.89 |
| ▸ | MAOA | P21397 | 3/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Genistein SCHEMBL19166 | 0.94 | MAPT (1.00) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL554056 | 0.94 | MAPT (1.00) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL29352944 | 0.94 | MAPT (1.00) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL10623004 | 0.93 | SMN1; SMN2 (0.94) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL551352 | 0.93 | MAPT (0.97) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL551449 | 0.93 | MAPT (0.97) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL551801 | 0.93 | MAPT (0.97) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| 5,7-Dihydroxyisoflavone SCHEMBL1586459 | 0.93 | MEN1 (1.00) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL31168045 | 0.93 | MAPT (0.97) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| Genistein SCHEMBL551402 | 0.93 | MAPT (0.97) | SMN1; SMN2RAB9AMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081491-A2 | NEW GENISTEIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | INSTYTUT FARMACEUTYCZNY (PL) | 2002-10-17 | — | — | WO | disclosed |