Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563358 | 1.00 | TACR2 (0.63) | TACR2TACR1 | |
| SCHEMBL7564297 | 0.84 | TACR2 (0.58) | TACR2TACR1 | |
| SCHEMBL7564301 | 0.84 | TACR2 (0.58) | TACR2TACR1 | |
| SCHEMBL7560046 | 0.80 | TACR2 (0.60) | TACR2TACR1 | |
| SCHEMBL7560035 | 0.80 | TACR2 (0.60) | TACR2TACR1 | |
| SCHEMBL7811978 | 0.80 | TACR2 (0.62) | TACR2TACR1 | |
| SCHEMBL6984664 | 0.77 | TACR1 (0.61) | TACR2TACR1 | |
| SCHEMBL3083325 | 0.76 | TACR2 (1.00) | TACR2TACR1 | |
| SCHEMBL3083322 | 0.76 | TACR2 (1.00) | TACR2TACR1 | |
| SCHEMBL5901167 | 0.72 | TACR1 (0.40) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888337-B1 | PIPERIDONE TACHYKININ ANTAGONISTS | PFIZER RES & DEV (IE) | 2002-06-05 | — | — | EP | disclosed |
| CN-1072666-C | (Azetidin-1-ylalkyl) lactams as tachykinin antagonists | PFIZER RES AND DEV CO N V S A (IE) | 2001-10-10 | — | — | CN | disclosed |
| US-6262075-B1 | Piperidone tachykinin antagonists | PFIZER INC | 2001-07-17 | — | — | US | disclosed |
| CN-1154699-A | (Azetidin-1-ylalkyl) lactams as tachykinin antagonists | PFIZER LTD (IE) | 1997-07-16 | — | — | CN | disclosed |