SCHEMBL7563383

SCHEMBL7563383

Cc1cc(NC(=O)Cc2cc(C(=N)N)ccc2O)ccc1-n1c(C)c(C)[nH]c1=O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.37
PRSS1 P07477 8/20 0.37
ANO1 Q5XXA6 4/20 0.36
F2 P00734 8/20 0.36
PLAU P00749 3/20 0.36
PLAT P00750 3/20 0.36
F9 P00740 1/20 0.35
F7 P08709 1/20 0.34
PLG P00747 2/20 0.34
KLK1 P06870 1/20 0.34
KLK5 Q9Y337 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6941617 0.99 F10 (0.37) F10PRSS1ANO1F2PLAU
Hydrochloric Acid SCHEMBL6939201 0.83 F2 (0.41) F10PRSS1F2F7
SCHEMBL7071377 0.78 KLK5 (0.41) F10PRSS1ANO1F2KLK1
Hydrochloric Acid SCHEMBL6943397 0.77 KLK5 (0.41) F10PRSS1ANO1F2KLK1
SCHEMBL7562464 0.76 KLK5 (0.42) F10PRSS1F2F7KLK1
SCHEMBL7562571 0.75 KLK5 (0.39) F10PRSS1ANO1F2F7
Hydrochloric Acid SCHEMBL7566109 0.75 KLK5 (0.39) F10PRSS1ANO1F2F7
SCHEMBL7569014 0.74 MEN1 (0.48) F10PRSS1F2F9KLK5
SCHEMBL7124379 0.74 ANO1 (0.44) F10PRSS1ANO1F2PLAU
Hydrochloric Acid SCHEMBL6939888 0.74 MEN1 (0.48) F10PRSS1F2F9KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US claimed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 F10 33/4885PRSS1 1106/4885ANO1 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.