Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743886 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRLGALS8KMT2AMAPT | |
| SCHEMBL7743883 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRLGALS8KMT2AMAPT | |
| SCHEMBL6020205 | 0.81 | NPC1 (0.39) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL7566181 | 0.77 | MEN1 (0.32) | KMT2AMEN1 | |
| SCHEMBL7563870 | 0.76 | PPARG (0.32) | ALDH1A1TSHRSMN1; SMN2KMT2AMAPT | |
| SCHEMBL7641953 | 0.73 | TSHR (0.38) | ALDH1A1TSHRSLC6A2TDP1CYP3A4 | |
| SCHEMBL9096127 | 0.73 | TSHR (0.38) | ALDH1A1TSHRSLC6A2TDP1CYP3A4 | |
| SCHEMBL9094442 | 0.72 | TSHR (0.30) | TSHR | |
| SCHEMBL16180090 | 0.72 | NEU3 (0.33) | ALDH1A1TSHRHSD17B10ALOX15SMN1; SMN2 | |
| SCHEMBL9094336 | 0.71 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233970-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001038337-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-31 | — | — | WO | disclosed |